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Immunoreactive trypsinogen : ウィキペディア英語版 | Immunoreactive trypsinogen Measurement of Immunoreactive trypsinogen (IRT) in blood of newborn babies is an assay in rapidly increasing use as a screening test for cystic fibrosis.〔(MedlinePlus Medical Encyclopedia: Neonatal cystic fibrosis screening )〕 IRT is typically raised in cystic fibrosis patients and is measured in routine heel-prick blood taken for biochemical screening of all newborn infants born in the UK. This testing is called the Guthrie Test. Samples with a raised IRT are then screened for common CF gene mutations, and infants with two mutations have a sweat test to confirm the diagnosis.〔Illustrated Textbook of Paediatrics, 4th Edition. Lissauer & Clayden. ISBN 978 0 7234 3565 5〕 Heterozygous carriers of cystic fibrosis can cause a raised IRT and it is therefore not diagnostic in isolation.〔Kumar & Clarks Clinical Medicine, 8th Edition. ISBN 978-0-7020-4499-1〕 ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Immunoreactive trypsinogen」の詳細全文を読む
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